Short answer

Yes. Active Matter has a dedicated PvE mode, so you can play without fighting other players. You can enter PvE alone or cooperatively, but the official FAQ warns that solo play is more difficult. Not every location supports every mode: some locations are reserved for PvPvE, PvP or PvE.

PvE questions answered

Question Official answer
Can I avoid PvP? Yes, by choosing dedicated PvE content.
Can I play solo? Yes, but solo is described as more hardcore than co-op.
Can I play co-op PvE? Yes.
Is Active Matter PvE-only? No. The game also has PvPvE extraction raids and dedicated PvP.
Can every location be played in PvE? No. Mode availability depends on the location.

PvE, PvPvE and PvP

PvE removes hostile player combat and lets you focus on creatures, anomalies, objectives and extraction. PvPvE combines those threats with other operatives. PvP is the dedicated player-versus-player option.

Choose PvE when you want to learn systems or avoid hostile players. Use the Raid Modes guide for the difference between raid types and the Solo and Co-op guide for group-play details.

What “PvE-only” does not mean

Dedicated PvE does not make the entire game PvE-only. The official FAQ states that mode access varies by location. A guide should therefore check the current raid-selection screen instead of promising that every map, objective or reward path is available in pure PvE.

The official sources do not publish one universal PvE limit, ticket count or reward multiplier for every version. Those values should be checked in the current client or patch notes before being quoted.